The CLF Protocol

Updated: 4/2022

There is much debate over what the root cause of disease is. Some say it’s lectins, oxalates, sugar, heavy metals, mold, non-native EMFs, parasites... the list goes on. 

The focus should really be on maximizing ATP production in the cell. There are three major things which accumulate in the tissues that get in the way of proper cellular energy production. They are: Calcification, Lipofuscin and Fibrosis. 

These should be the starting place for optimizing your health. Without a knowledge of these, you may experience alleviation of symptoms but it will only be temporary. They can come back years later full-bore and amplified.

Without proper cellular respiration, the cells cannot generate a sufficient quantity of carbon dioxide (CO2), infrared light (heat), water (H2O) and, ultimately, adenosine triphosphate, the energy currency of the body.

CO2, IR light, and water each work together in a beautiful symphony to support every system in our entire body: muscular, skeletal, lymphatic, endocrine, nervous, everything! 

When the cells in an organ or gland cannot generate energy, the tissue in that area atrophies and dies. When this happens in the thyroid gland we get thyroid production problems. When this happens in the liver we get detoxification (glucaronidation/sulfation) and thyroid conversion (T4 -> T3) problems. When this happens in the pancreas we have problems properly metabolizing carbohydrate/sugar, the primary fuel of the human body. 

It is easy to see how these tissues getting clogged can compound and interfere with the production, transport and utilization of countless thousands of chemical messengers that conduct the beautiful and delicate symphony of our body. 

The CLF Protocol is designed to address the root cause of every illness by taking into consideration multiple factors including but not limited to: the industrial revolution (acid rain), NPK fertilizer (organic food isn't as pure as you think), the iron fortification program (started after WWII), the force feeding of concentrated PUFAs (polyunsaturated fats/vegetable oils/omega-3s) and unnaturally elevated ingestion of Advanced Glycation End Products (AGEs). 


Did you know that you have a coral reef in your tissues? That's a a large part of why it hurts when someone steps on you or pinches you. Any tissue which has excess calcium is stressed and necrotic; oxygen cannot get to the tissue so the tissue dies.

Calcium and potassium are magnesium antagonists.

What is deficient across the board in all human beings is magnesium.

The cause:

The fertilizer that feeds the entire planet was switched in the mid 1850s in Germany when the powers-that-be saw the perfect opportunity to jump start the military-medical-petrochemical-pharmaceutical cartel and poison the whole planet. This was their primary method to mentally handicap the population was NPK fertilizer and agriculture lime (calcium hydroxide) promoted and later recanted by Justice Von Liebig.

The solution:

To reverse the calcification, magnesium must be consumed daily.

The amount of magnesium we require is dependent upon the degree of chronic oxidative stress induced by iron overload and the resulting calcification, lipofuscin and fibrosis. 

Most people are not consuming enough magnesium and/or the right forms. Oxide, citrate and carbonate should be avoided.

I like getting my magnesium in three ways:

1) homemade magnesium bicarbonate (don't waste your money buying pre-made stuff)

2) amino acid bound forms of magnesium (glycinate and taurate). See Mag-ATP product

3) magnesium baths in magnesium sulfate and magnesium chloride every week

When we combine all three of these while being conscious to lower our magnesium burn rate we can finally start to restore the proper levels of magnesium in the red blood cell. This can be tracked using an "RBC magnesium" test. Standard serum magnesium tests are useless and do not reflect our true magnesium statu

Vitamin K2, a fat soluble essential vitamin, is deficient in most people and extremely effective at reversing calcification. There is not enough K2 in the food to reverse the damage. 

Purely K is a combination of K1, K2-4 and K2-7 without cofactors such as zinc or vitamin D. This is a safe way to acquire K2-7. Get your zinc from grassfed ruminant animals and oysters and hormone D from ultraviolet light, not a supplement. 

Shilajit is a 15 million+ year old condensed ecosystem in a tar-like form. It contains all 84+ known and unknown carbon-bonded organic minerals and also fulvic acid.

Plants are supposed to (and used to) secrete fulvic acid in order to bond to positively-charged metals and form organic carbon-based mineral structures. That does not happen anymore due to acid rain overpowering it. Everybody is deficient in trace minerals and overloaded with calcium oxalate crystals in the tissues. Shilajit is therefore both a complete mineral source, comprised of 90% magnesium, potassium and sodium, and a potent dissolver of excess calcium in the body. 

Mitolife offers a convenient compressed tablet form of shilajit. For anyone that's taken the resin in the jar, they know that it tastes horrible! With Mitolife Panacea, you can just swallow the tablets whole. I take a minimum of five a day (1 gram), usually with a glass of raw milk; that is how it was traditionally consumed in India.

Start drinking low TDS, filtered water. Avoid countertop units and opt for reverse osmosis filtration under your kitchen sink that is ideally mineralized at the end. If you don't have remineralization, add a pinch of white salt to your water and let it dissolve to remineralize it. 

I use a whole house system from Flow Motion that adds back in magnesium bicarbonate at the end of the process.



Have you ever looked at an older person's arms and forehead and seen freckle-looking spots all over the place? Those aren't freckles; they are "omega-3 barcodes" as Atom Bergstrom calls them that indicates lipofuscin poisoning.

For every one age spot/ceroid pigment visible on the skin there are up to 100,000 present below the tissue. Often we do not need a blood test to figure out what we have wrong with us. In the case of lipofuscin, all you need to do is take off your clothes and see it. They are most often visible in areas that get the most sunlight (forehead, forearms). 

What caused it?

It was a one-two punch of iron and omega-3 fatty acid concentrates which gave nearly every human being on the planet lipofuscinosis. 

HUFAs, highly unsaturated fatty acids, or omega-3s, in highly concentrated extract form such as fish oil and canola oil, increase the production of estrogen by affecting sex steroid binding protein (SSBG), which exacerbates the lipofuscin problem.

Aluminum is the third most common element in the Earth's crust. Drinking out of aluminum cans (filled with sulfuric acid), melted cheese, processed foods, and even organic produce grown in poorly managed soil are all sources of aluminum that contribute to lipofuscin. 


Burning fossil fuels created acid rain which liberates iron in excess amounts from the earth and poisons our rivers, lakes and springs. Spring and well water is now loaded with sulfuric and nitric acid and excess iron and aluminum.

Iron fortified grains, processed food, and vegetables expedited the process of saturating everyone's tissues with iron that the body has no way to get rid of. There are 5 doorways for iron to get into the cell and only one for it to get out, ferroportin, which is a copper dependent doorway. Iron depletes copper and copper deficiency contributes to lipofuscin.


The fish oil industry has been very successful in their marketing campaign to convince us that omega-3 fatty acids (DHA, EPA, and ALA) are needed in large amounts for human health and fetal development. This is not true. When consumed in excess they contribute to cancer, heart disease, diabetes, Alzheimer's, anxiety, depression, insomnia and accelerated aging. 

The public was never told that when the Burrs discovered omega-3s, zinc, selenium and most of the B vitamins had not been discovered yet. The conclusions that they made about their essentiality was based on an incomplete picture and they ran with it, pawning off toxic oils that were previously used as varnish to paint walls.

Omega-3 fatty acids are highly unsaturated fatty acids with multiple double bonds which easily oxidize in an iron overloaded warm body. This is a primary cause of chronic inflammation.

Being overly saturated with iron in your tissues is a way to guarantee that you're mismanaging the oxygen that you breathe. The chemical reactions that occur when we cannot turn hydrogen peroxide into water in complex IV of our mitochondria are like a domino effect that contributes massively to these accumulations (CLF). 

It doesn't matter how perfectly preserved the fish, krill, algae, or seal oil is. An argument against consumed concentrated PUFAs is that most of the products are oxidized before you ingest them. That doesn't matter at all. Taking 10, 20, 30, 40, 50 grams of fish oil daily will give you disease. That is an unnatural amount of omega-3s, way more than the 4-6% we get from our diet.

Excess iron activates ALOX enzymes (there's 8 of them) which ADD oxygen to PUFAs. Excess aluminum in the body further spreads lipofuscin, as does ultraviolet light. 

What if I came into your bedroom where you repair and rest and trashed the place? What if I filled up 70% of your bedroom with garbage? Could you get a good nights sleep if your room was full of trash? No, and your cells can't either. Lipofuscin cakes up the lysosomes of your cell which are responsible for the trending process of autophagy. 

Guess where copper is stored in the body? In the lysosomes! Maybe copper deficiency is a primary driver behind lipofuscin? 

Autophagy cannot happen with lipofuscin in your body. In other words, detoxification is impossible. All of the intermittent fasters trying to force this process are shooting themselves in the foot. 

The solution:

Get an oil change with saturated animal fats, take vitamin E, and utilize red light therapy.

Polyunsaturated fats, especially HIGHLY unsaturated fats (omega-3), increase the requirement for Vitamin E by six times. For a detailed write-up of Vitamin E in relation to PUFAs, head over to my product page for PUFA Protect. 

Vitamin E is a fat soluble vitamin and chain breaking antioxidant which stops the process of lipid peroxidation in the cell once its started. It stops the domino effect in its tracks. It is both a short and long-term solution to the overconsumption of PUFAs. Start with one a day for awhile and see how you react to it before you increase your dosage.

Consume more saturated than unsaturated fats. This means red meat, raw dairy, pastured eggs, coconut oil, ghee and butter. These are all dominant in saturated fat which help to replace the unsaturated fat that is stored in your tissue from all of the canola oil you were fed growing up. Avoid fish oil, algae oil, krill oil, and tell all of your friends to throw them in the trash.

Cod liver oil that is unfermented and unfortified is the exception because of its outstanding retinol (vitamin A) content which prevents and reverses calcifcation, lipofuscin and fibrosis. 

Consume a minimum of 3 pastured eggs a day (soft boiled or sunny side up) to get 300mg of choline which supports the liver detoxification of omega-3 fatty acid breakdown products (acrolein, aldehydes, etc). 

Endotoxin increases the rate of iron oxidation by 23 times. Oxidized iron quickly combines with PUFAs (liberated through fasting or stress) to form lipofuscin. I take two capsules of spore based probiotics everyday to keep my endotoxin load down.

Red light therapy has been found to protect the skin from ultraviolet light and radiation-induced damage in general. I would not expose PUFA-loaded skin to unlimited amounts of sunlight. You cook like a lobster. I use a GembaRed light for twenty minutes a day, minimum, which has systemic benefits and prevents damage from lipofuscin.


Fibrosis is another word for scar tissue. Fibrosis consists of fibrin, a spiders-web looking material that results from tissue damage. Tissue damage occurs when cellular respiration isn't happening efficiently.

Fibrin build-up is responsible for tight muscles and the loss of flexibility. Over time it shrinks organs and glands, reducing their ability to function properly. Ultimately the result is even less ATP (cellular energy) being produced.

Fibrosis is the end result of iron overload, calcification, and lipofuscin.

Irritation -> Inflammation -> Scar Tissue Formation

This is the deepest layer of detoxification and one that is often overlooked.

What caused it?

Anything that inhibits oxygen from getting to the cell causes tissue damage and scarring. 

Calcification and lipofuscin directly cause tissue damage by shutting down electron chain transport (ECT) and cellular respiration. The cells choke and cannot breathe. This results in a build-up of lactic acid instead of pyruvic acid which is the hallmark of stress and cancer.

The solution:

Bodywork and Systemic Enzyme Therapy

Manual therapy (deep tissue massage) by an experienced practitioner or with your partner is essential to break up fibrotic tissue and restore the flow of oxygen. Tools such as the Rapid Release Technology are very beneficial if you're by yourself.

Nattokinase and serrapeptase are two proteolytic enzymes which have been found in clinical research to work together and dissolve fibrin throughout the body. I take 3-6 capsules of Mitolife Dissolve It All when I wake up. They are ideal to take on an empty stomach. The plastic-free capsule doesn't open until it reaches the small intestine. You must take the capsules whole. They circulate in the body for 6-10 hours dissolving fibrosis. 

By restoring oxygen to every tissue, systemic enzymes can have powerful effects. The benefits are systemic! I have received countless testimonials about skin conditions improving and cysts (endometriosis) and back pain decreasing. 

To be continued:

This protocol is a work-in-progress and is by no means complete. In fact, it will never be complete as new understandings emerge. 

To stay up to date on my latest findings, listen to my podcast Mitolife Radio. It is available on YouTube, Spotify, iTunes and Stitcher.

Lets get supercharged!

-Matt Blackburn